| Rank | Player | Plate Appearances | Years | ||
| 1. | Pete Rose | 15861 | 1963-1986 | ||
| 2. | Carl Yastrzemski* | 13991 | 1961-1983 | ||
| 3. | Hank Aaron* | 13940 | 1954-1976 | ||
| 4. | Rickey Henderson | 13346 | 1979-2003 | ||
| 5. | Ty Cobb* | 13072 | 1905-1928 | ||
| 6. | Cal Ripken* | 12883 | 1981-2001 | ||
| 7. | Eddie Murray* | 12817 | 1977-1997 | ||
| 8. | Stan Musial* | 12712 | 1941-1963 | ||
| 9. | Barry Bonds | 12606 | 1986-2007 | ||
| 10. | Craig Biggio | 12503 | 1988-2007 | ||
| 11. | Willie Mays* | 12493 | 1951-1973 | ||
| 12. | Dave Winfield* | 12358 | 1973-1995 | ||
| 13. | Robin Yount* | 12249 | 1974-1993 | ||
| 14. | Paul Molitor* | 12160 | 1978-1998 | ||
| 15. | Rafael Palmeiro | 12046 | 1986-2005 | ||
| 16. | Eddie Collins* | 12037 | 1906-1930 | ||
| 17. | Tris Speaker* | 11988 | 1907-1928 | ||
| 18. | Brooks Robinson* | 11782 | 1955-1977 | ||
| 19. | Frank Robinson* | 11743 | 1956-1976 | ||
| 20. | Honus Wagner* | 11739 | 1897-1917 | ||
| 21. | George Brett* | 11624 | 1973-1993 | ||
| 22. | Al Kaline* | 11597 | 1953-1974 | ||
| 23. | Reggie Jackson* | 11416 | 1967-1987 | ||
| 24. | Mel Ott* | 11337 | 1926-1947 | ||
| 25. | Joe Morgan* | 11329 | 1963-1984 | ||
| 26. | Cap Anson* | 11319 | 1871-1897 | ||
| 27. | Rabbit Maranville* | 11256 | 1912-1935 | ||
| 28. | Lou Brock* | 11235 | 1961-1979 | ||
| 29. | Luis Aparicio* | 11230 | 1956-1973 | ||
| 30. | Rusty Staub | 11229 | 1963-1985 | ||
| 31. | Harold Baines | 11092 | 1980-2001 | ||
| 32. | Omar Vizquel | 11082 | 1989-2008 | ||
| 33. | Tony Perez* | 10861 | 1964-1986 | ||
| 34. | Ozzie Smith* | 10778 | 1978-1996 | ||
| 35. | Max Carey* | 10770 | 1910-1929 | ||
| 36. | Andre Dawson | 10769 | 1976-1996 | ||
| 37. | Paul Waner* | 10763 | 1926-1945 | ||
| 38. | Ken Griffey | 10742 | 1989-2008 | ||
| 39. | Wade Boggs* | 10740 | 1982-1999 | ||
| 40. | Darrell Evans | 10737 | 1969-1989 | ||
| 41. | Gary Sheffield | 10635 | 1988-2008 | ||
| 42. | Babe Ruth* | 10617 | 1914-1935 | ||
| 43. | Sam Crawford* | 10594 | 1899-1917 | ||
| 44. | Dwight Evans | 10569 | 1972-1991 | ||
| 45. | Rod Carew* | 10550 | 1967-1985 | ||
| 46. | Luis Gonzalez | 10531 | 1990-2008 | ||
| 47. | Billy Williams* | 10519 | 1959-1976 | ||
| 48. | Jake Beckley* | 10470 | 1888-1907 | ||
| 49. | Steve Finley | 10460 | 1989-2007 | ||
| Nap Lajoie* | 10460 | 1896-1916 | |||
| 50. | Vada Pinson | 10403 | 1958-1975 | ||
| 51. | Roberto Alomar | 10400 | 1988-2004 | ||
| 52. | Ernie Banks* | 10395 | 1953-1971 | ||
| 53. | Bill Dahlen | 10390 | 1891-1911 | ||
| 54. | Tim Raines | 10359 | 1979-2002 | ||
| 55. | Nellie Fox* | 10349 | 1947-1965 | ||
| 56. | Sam Rice* | 10246 | 1915-1934 | ||
| 57. | Harry Hooper* | 10244 | 1909-1925 | ||
| 58. | Luke Appling* | 10243 | 1930-1950 | ||
| 59. | Charlie Gehringer* | 10237 | 1924-1942 | ||
| 60. | Tony Gwynn* | 10232 | 1982-2001 | ||
| 61. | Graig Nettles | 10226 | 1967-1988 | ||
| 62. | Roberto Clemente* | 10212 | 1955-1972 | ||
| 63. | Dave Parker | 10184 | 1973-1991 | ||
| 64. | Fred McGriff | 10174 | 1986-2004 | ||
| 65. | George Davis* | 10151 | 1890-1909 | ||
| 66. | Eddie Mathews* | 10101 | 1952-1968 | ||
| 67. | Frankie Frisch* | 10100 | 1919-1937 | ||
| 68. | Frank Thomas | 10074 | 1990-2008 | ||
| 69. | Mike Schmidt* | 10062 | 1972-1989 | ||
| 70. | Bill Buckner | 10033 | 1969-1990 | ||
| 71. | Buddy Bell | 10009 | 1972-1989 | ||
| 72. | Zack Wheat* | 9996 | 1909-1927 | ||
| Chili Davis | 9996 | 1981-1999 | |||
| 73. | Lou Whitaker | 9967 | 1977-1995 | ||
| 74. | Doc Cramer | 9933 | 1929-1948 | ||
| 75. | Mickey Mantle* | 9909 | 1951-1968 | ||
| 76. | Sammy Sosa | 9896 | 1989-2007 | ||
| 77. | Carlton Fisk* | 9853 | 1969-1993 | ||
| 78. | Mickey Vernon | 9834 | 1939-1960 | ||
| 79. | Harmon Killebrew* | 9831 | 1954-1975 | ||
| 80. | Goose Goslin* | 9822 | 1921-1938 | ||
| Willie Davis | 9822 | 1960-1979 | |||
| 81. | Fred Clarke* | 9819 | 1894-1915 | ||
| 82. | Gary Gaetti | 9817 | 1981-2000 | ||
| 83. | Ted Williams* | 9791 | 1939-1960 | ||
| 84. | Al Oliver | 9778 | 1968-1985 | ||
| 85. | Richie Ashburn* | 9736 | 1948-1962 | ||
| 86. | Julio Franco | 9731 | 1982-2007 | ||
| 87. | Lave Cross | 9710 | 1887-1907 | ||
| 88. | Willie McCovey* | 9686 | 1959-1980 | ||
| 89. | Ted Simmons | 9685 | 1968-1988 | ||
| 90. | Jimmie Foxx* | 9670 | 1925-1945 | ||
| 91. | Lou Gehrig* | 9660 | 1923-1939 | ||
| 92. | Dave Concepcion | 9640 | 1970-1988 | ||
| 93. | Bert Campaneris | 9625 | 1964-1983 | ||
| 94. | Bobby Wallace* | 9612 | 1894-1918 | ||
| 95. | Jesse Burkett* | 9605 | 1890-1905 | ||
| 96. | Willie Keeler* | 9594 | 1892-1910 | ||
| 97. | Brett Butler | 9545 | 1981-1997 |