| Rank | Player | Sacrifice Flies | Years | ||
| 1. | Eddie Collins* | 512 | 1906-1930 | ||
| 2. | Jake Daubert | 392 | 1910-1924 | ||
| 3. | Stuffy McInnis | 383 | 1909-1927 | ||
| 4. | Willie Keeler* | 350 | 1892-1910 | ||
| 5. | Donie Bush | 337 | 1908-1923 | ||
| 6. | Ray Chapman | 334 | 1912-1920 | ||
| 7. | Bill Wambsganss | 323 | 1914-1926 | ||
| 8. | Roger Peckinpaugh | 314 | 1910-1927 | ||
| 9. | Larry Gardner | 311 | 1908-1924 | ||
| 10. | Tris Speaker* | 309 | 1907-1928 | ||
| 11. | Rabbit Maranville* | 300 | 1912-1935 | ||
| 12. | Ty Cobb* | 295 | 1905-1928 | ||
| 13. | Max Carey* | 290 | 1910-1929 | ||
| 14. | Jimmy Sheckard | 286 | 1897-1913 | ||
| 15. | Joe Tinker* | 285 | 1902-1916 | ||
| 16. | Jack Barry | 284 | 1908-1919 | ||
| 17. | Frank Schulte | 279 | 1904-1918 | ||
| 18. | Jimmy Austin | 278 | 1909-1929 | ||
| 19. | Harry Heilmann* | 277 | 1914-1932 | ||
| 20. | Joe Sewell* | 275 | 1920-1933 | ||
| Fred Tenney | 275 | 1894-1911 | |||
| Everett Scott | 275 | 1914-1926 | |||
| 21. | Wally Pipp | 272 | 1913-1928 | ||
| 22. | Bobby Veach | 271 | 1912-1925 | ||
| 23. | Dick Bartell | 269 | 1927-1946 | ||
| 24. | Terry Turner | 268 | 1901-1919 | ||
| 25. | George Cutshaw | 266 | 1912-1923 | ||
| 26. | Otto Knabe | 265 | 1905-1916 | ||
| 27. | Duffy Lewis | 264 | 1910-1921 | ||
| 28. | Howie Shanks | 263 | 1912-1925 | ||
| 29. | Sherry Magee | 260 | 1904-1919 | ||
| 30. | Ossie Vitt | 259 | 1912-1921 | ||
| 31. | Shano Collins | 258 | 1910-1925 | ||
| 32. | Joe Judge | 257 | 1915-1934 | ||
| 33. | Johnny Evers* | 256 | 1902-1929 | ||
| Edd Roush* | 256 | 1913-1931 | |||
| 34. | Fielder Jones | 254 | 1896-1915 | ||
| 35. | Ed Konetchy | 253 | 1907-1921 | ||
| Bill Bradley | 253 | 1899-1915 | |||
| 36. | Bucky Harris* | 249 | 1919-1931 | ||
| 37. | Harry Steinfeldt | 248 | 1898-1911 | ||
| 38. | Harry Hooper* | 247 | 1909-1925 | ||
| 39. | Buck Weaver | 242 | 1912-1920 | ||
| 40. | Sam Crawford* | 241 | 1899-1917 | ||
| 41. | Tommy Leach | 240 | 1898-1918 | ||
| 42. | Willie Kamm | 238 | 1923-1935 | ||
| 43. | Omar Vizquel | 235 | 1989-2008 | ||
| Dots Miller | 235 | 1909-1921 | |||
| 44. | Milt Stock | 234 | 1913-1926 | ||
| 45. | Del Pratt | 233 | 1912-1924 | ||
| 46. | Hans Lobert | 231 | 1903-1917 | ||
| Pie Traynor* | 231 | 1920-1937 | |||
| 47. | Frankie Frisch* | 229 | 1919-1937 | ||
| 48. | Jimmie Dykes | 228 | 1918-1939 | ||
| 49. | Mule Haas | 227 | 1925-1938 | ||
| 50. | George McBride | 226 | 1901-1920 | ||
| George Sisler* | 226 | 1915-1930 | |||
| 51. | Claude Ritchey | 224 | 1897-1909 | ||
| Dode Paskert | 224 | 1907-1921 | |||
| Fred Clarke* | 224 | 1894-1915 | |||
| 52. | Honus Wagner* | 221 | 1897-1917 | ||
| Nap Lajoie* | 221 | 1896-1916 | |||
| 53. | Wally Gerber | 219 | 1914-1929 | ||
| Charlie Grimm | 219 | 1916-1936 | |||
| Dick Hoblitzel | 219 | 1908-1918 | |||
| Amos Strunk | 219 | 1908-1924 | |||
| 54. | Ossie Bluege | 218 | 1922-1939 | ||
| 55. | Mickey Doolan | 217 | 1905-1918 | ||
| 56. | Rogers Hornsby* | 216 | 1915-1937 | ||
| Buck Herzog | 216 | 1908-1920 | |||
| Hal Chase | 216 | 1905-1919 | |||
| 57. | Ozzie Smith* | 214 | 1978-1996 | ||
| Ray Schalk* | 214 | 1912-1929 | |||
| 58. | Tom Glavine | 213 | 1987-2008 | ||
| Sam Rice* | 213 | 1915-1934 | |||
| 59. | Dave Bancroft* | 212 | 1915-1930 | ||
| 60. | Bing Miller | 210 | 1921-1936 | ||
| 61. | Nellie Fox* | 208 | 1947-1965 | ||
| Kid Gleason | 208 | 1888-1912 | |||
| 62. | Tom Jones | 205 | 1902-1910 | ||
| 63. | Freddy Parent | 203 | 1899-1911 | ||
| 64. | Frank Isbell | 202 | 1898-1909 | ||
| 65. | Bert Campaneris | 199 | 1964-1983 | ||
| 66. | Marty McManus | 198 | 1920-1934 | ||
| Ivy Olson | 198 | 1911-1924 | |||
| 67. | Danny Murphy | 197 | 1900-1915 | ||
| 68. | Larry Doyle | 195 | 1907-1920 | ||
| 69. | Lee Magee | 194 | 1911-1919 | ||
| 70. | Phil Rizzuto* | 193 | 1941-1956 | ||
| 71. | Miller Huggins* | 192 | 1904-1916 | ||
| Monte Cross | 192 | 1892-1907 | |||
| 72. | Earl Sheely | 189 | 1921-1931 | ||
| 73. | Bibb Falk | 188 | 1920-1931 | ||
| Clyde Milan | 188 | 1907-1922 | |||
| 74. | Hy Myers | 187 | 1909-1925 | ||
| George Burns | 187 | 1914-1929 | |||
| Hughie Critz | 187 | 1924-1935 | |||
| 75. | Harry Lord | 186 | 1907-1915 | ||
| Heinie Manush* | 186 | 1923-1939 | |||
| 76. | Doc Johnston | 184 | 1909-1922 |