| Rank | Player | OBP | Year | Age | ||
| 1. | Barry Bonds | .609 | 2004 | 39 | ||
| 2. | Barry Bonds | .582 | 2002 | 37 | ||
| 3. | Ted Williams* | .553 | 1941 | 22 | ||
| 4. | John McGraw* | .547 | 1899 | 26 | ||
| 5. | Babe Ruth* | .545 | 1923 | 28 | ||
| 6. | Babe Ruth* | .532 | 1920 | 25 | ||
| 7. | Barry Bonds | .529 | 2003 | 38 | ||
| 8. | Ted Williams* | .526 | 1957 | 38 | ||
| 9. | Billy Hamilton* | .523 | 1894 | 28 | ||
| 10. | Babe Ruth* | .516 | 1926 | 31 | ||
| 11. | Barry Bonds | .515 | 2001 | 36 | ||
| 12. | Ted Williams* | .513 | 1954 | 35 | ||
| 13. | Babe Ruth* | .513 | 1924 | 29 | ||
| 14. | Babe Ruth* | .512 | 1921 | 26 | ||
| 15. | Mickey Mantle* | .512 | 1957 | 25 | ||
| 16. | Rogers Hornsby* | .507 | 1924 | 28 | ||
| 17. | Joe Kelley* | .502 | 1894 | 22 | ||
| 18. | Hugh Duffy* | .502 | 1894 | 27 | ||
| 19. | Ed Delahanty* | .500 | 1895 | 27 | ||
| 20. | Ted Williams* | .499 | 1942 | 23 | ||
| 21. | Ted Williams* | .499 | 1947 | 28 | ||
| 22. | Rogers Hornsby* | .498 | 1928 | 32 | ||
| 23. | Ted Williams* | .497 | 1946 | 27 | ||
| 24. | Ted Williams* | .497 | 1948 | 29 | ||
| 25. | Bill Joyce | .496 | 1894 | 28 | ||
| 26. | Babe Ruth* | .495 | 1931 | 36 | ||
| 27. | Babe Ruth* | .493 | 1930 | 35 | ||
| 28. | Arky Vaughan* | .491 | 1935 | 23 | ||
| 29. | Ted Williams* | .490 | 1949 | 30 | ||
| 30. | Billy Hamilton* | .490 | 1895 | 29 | ||
| 31. | Billy Hamilton* | .490 | 1893 | 27 | ||
| 32. | Tip O'Neill | .490 | 1887 | 29 | ||
| 33. | Babe Ruth* | .489 | 1932 | 37 | ||
| 34. | Rogers Hornsby* | .489 | 1925 | 29 | ||
| 35. | Frank Thomas | .487 | 1994 | 26 | ||
| 36. | Norm Cash | .487 | 1961 | 26 | ||
| 37. | Ty Cobb* | .486 | 1915 | 28 | ||
| 38. | Babe Ruth* | .486 | 1927 | 32 | ||
| 39. | Jesse Burkett* | .486 | 1895 | 26 | ||
| 40. | Tris Speaker* | .483 | 1920 | 32 | ||
| 41. | King Kelly* | .483 | 1886 | 28 | ||
| 42. | Harry Heilmann* | .481 | 1923 | 28 | ||
| 43. | Billy Hamilton* | .480 | 1898 | 32 | ||
| 44. | Ted Williams* | .479 | 1956 | 37 | ||
| 45. | Tris Speaker* | .479 | 1925 | 37 | ||
| 46. | Edgar Martinez | .479 | 1995 | 32 | ||
| 47. | Ed Delahanty* | .478 | 1894 | 26 | ||
| 48. | Lou Gehrig* | .478 | 1936 | 32 | ||
| 49. | Billy Hamilton* | .477 | 1896 | 30 | ||
| 50. | Jason Giambi | .477 | 2001 | 30 | ||
| 51. | Jason Giambi | .476 | 2000 | 29 | ||
| 52. | Wade Boggs* | .476 | 1988 | 29 | ||
| 53. | Cupid Childs | .475 | 1894 | 26 | ||
| 54. | John McGraw* | .475 | 1898 | 25 | ||
| 55. | Harry Heilmann* | .475 | 1927 | 32 | ||
| 56. | Tris Speaker* | .474 | 1922 | 34 | ||
| 57. | Lou Gehrig* | .474 | 1927 | 23 | ||
| 58. | Luke Appling* | .474 | 1936 | 29 | ||
| 59. | Lou Gehrig* | .473 | 1930 | 26 | ||
| 60. | Lou Gehrig* | .473 | 1937 | 33 | ||
| 61. | John Olerud | .473 | 1993 | 24 | ||
| 62. | Hughie Jennings* | .472 | 1896 | 27 | ||
| 63. | Ed Delahanty* | .472 | 1896 | 28 | ||
| 64. | John McGraw* | .471 | 1897 | 24 | ||
| 65. | Dan Brouthers* | .471 | 1891 | 33 | ||
| 66. | Chipper Jones | .470 | 2008 | 36 | ||
| 67. | Tris Speaker* | .470 | 1916 | 28 | ||
| 68. | Bill Joyce | .470 | 1896 | 30 | ||
| 69. | Mark McGwire | .470 | 1998 | 34 | ||
| 70. | Carlos Delgado | .470 | 2000 | 27 | ||
| 71. | Joe Kelley* | .469 | 1896 | 24 | ||
| 72. | Tris Speaker* | .469 | 1923 | 35 | ||
| 73. | Jimmie Foxx* | .469 | 1932 | 24 | ||
| 74. | Todd Helton | .469 | 2004 | 30 | ||
| 75. | Jesse Burkett* | .468 | 1897 | 28 | ||
| 76. | Ty Cobb* | .468 | 1925 | 38 | ||
| 77. | Joe Jackson | .468 | 1911 | 21 | ||
| 78. | Lou Gehrig* | .467 | 1928 | 24 | ||
| 79. | Ty Cobb* | .467 | 1913 | 26 | ||
| 80. | Mark McGwire | .467 | 1996 | 32 | ||
| 81. | George Sisler* | .467 | 1922 | 29 | ||
| 82. | Mike Griffin | .467 | 1894 | 29 | ||
| 83. | Cupid Childs | .467 | 1896 | 28 | ||
| 84. | Ty Cobb* | .467 | 1911 | 24 | ||
| 85. | Joe Morgan* | .466 | 1975 | 31 | ||
| 86. | Dan Brouthers* | .466 | 1890 | 32 | ||
| 87. | Lou Gehrig* | .466 | 1935 | 31 | ||
| 88. | Gary Sheffield | .465 | 1996 | 27 | ||
| 89. | Lou Gehrig* | .465 | 1934 | 30 | ||
| 90. | Lefty O'Doul | .465 | 1929 | 32 | ||
| 91. | Jimmie Foxx* | .464 | 1939 | 31 | ||
| 92. | Tris Speaker* | .464 | 1912 | 24 | ||
| 93. | Ed Delahanty* | .464 | 1899 | 31 | ||
| 94. | Pete Browning | .464 | 1887 | 25 | ||
| 95. | Mickey Mantle* | .464 | 1956 | 24 | ||
| 96. | Edgar Martinez | .464 | 1996 | 33 | ||
| 97. | Ted Williams* | .464 | 1951 | 32 | ||
| 98. | Willie Keeler* | .464 | 1897 | 25 | ||
| 99. | Todd Helton | .463 | 2000 | 26 | ||
| 100. | Cupid Childs | .463 | 1893 | 25 |